A Case of Osteomalacia: The Pivotal role of the Non-Decalcified Bone Biopsy

A postmenopausal osteopenic woman presented with recurrent stress fractures of the feet and normal parameters of mineral homeostasis. Despite the absence of biochemical or radiographic evidence, severe osteomalacia was documented by histomorphometric analysis of a tetracycline labeled, non-decalcifi...

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Detalles Bibliográficos
Autores principales: Kim, Ghi Su, Bergfeld, Michele A., Avioli, Louis V., Teitelbaum, Steven L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association of Internal Medicine 1988
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534953/
https://www.ncbi.nlm.nih.gov/pubmed/3154190
http://dx.doi.org/10.3904/kjim.1988.3.2.132
Descripción
Sumario:A postmenopausal osteopenic woman presented with recurrent stress fractures of the feet and normal parameters of mineral homeostasis. Despite the absence of biochemical or radiographic evidence, severe osteomalacia was documented by histomorphometric analysis of a tetracycline labeled, non-decalcified bone biopsy. This observation underscores the need for specific bone biopsy confirmation of skeletal disease in patients with fracture-prone osteopenia.

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