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Circulating HBsAg/IgG Complexes in idiopathic Chronic Glomerulonephritis
We measured HBsAg/IgG complexes (CX) quantitatively by ELISA from HBsAg positive serum of 35 liver disease patients, 15 patients with glomerular diseases (8 membranous glomerulonephritis (MGN) 7 membarnoproliferative glomerulonephritis (MPGN)), and 50 healthy carriers of HBsAg. HbsAg/IgG CX was dete...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Association of Internal Medicine
1991
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535014/ https://www.ncbi.nlm.nih.gov/pubmed/1742252 http://dx.doi.org/10.3904/kjim.1991.6.1.21 |
Sumario: | We measured HBsAg/IgG complexes (CX) quantitatively by ELISA from HBsAg positive serum of 35 liver disease patients, 15 patients with glomerular diseases (8 membranous glomerulonephritis (MGN) 7 membarnoproliferative glomerulonephritis (MPGN)), and 50 healthy carriers of HBsAg. HbsAg/IgG CX was detected in 26 out of 35 liver disease patients (74.3%), 5 out of 50 healthy carriers (10%), and one of both 8 MGN patients (12.5%) and 7 MPGN patients (14.3%). HBsAg/IgG CX was big in size and wide spreaded in the liver disease groups but negligible in the healthy carrier group (41±2.6 ng/ml, n=5) and MGN (50 ng/ml n=1) and MPGN (42 ng/ml, n=1) group. In the liver disease group, no one suffered from glomerulopathy even with a wide spectrum of HBsAg/IgG CX. These results suggest that HBsAg/IgG CX in plasma is non causative of MGN and MPGN. |
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