Elevated β-catenin pathway as a novel target for patients with resistance to EGF receptor targeting drugs

There is a high death rate of lung cancer patients. Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) are effective in some lung adenocarcinoma patients with EGFR mutations. However, a significant number of patients show primary and acquire resistance to EGFR-TKIs. Although the...

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Detalles Bibliográficos
Autores principales: Nakata, Asuka, Yoshida, Ryo, Yamaguchi, Rui, Yamauchi, Mai, Tamada, Yoshinori, Fujita, Andre, Shimamura, Teppei, Imoto, Seiya, Higuchi, Tomoyuki, Nomura, Masaharu, Kimura, Tatsuo, Nokihara, Hiroshi, Higashiyama, Masahiko, Kondoh, Kazuya, Nishihara, Hiroshi, Tojo, Arinobu, Yano, Seiji, Miyano, Satoru, Gotoh, Noriko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535059/
https://www.ncbi.nlm.nih.gov/pubmed/26268703
http://dx.doi.org/10.1038/srep13076

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