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Preconditioning of bone marrow mesenchymal stem cells by prolyl hydroxylase inhibition enhances cell survival and angiogenesis in vitro and after transplantation into the ischemic heart of rats

INTRODUCTION: Poor cell survival and limited functional benefits have restricted the efficacy of bone marrow mesenchymal stem cells (BMSCs) in the treatment of myocardial infarction. We showed recently that hypoxia preconditioning of BMSCs and neural progenitor cells before transplantation can enhan...

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Detalles Bibliográficos
Autores principales: Liu, Xian-Bao, Wang, Jian-An, Ji, Xiao-Ya, Yu, Shan Ping, Wei, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535299/
https://www.ncbi.nlm.nih.gov/pubmed/25257482
http://dx.doi.org/10.1186/scrt499