A putative, novel coli surface antigen 8B (CS8B) of enterotoxigenic Escherichia coli

Enterotoxigenic Escherichia coli (ETEC) strains harbor multiple fimbriae and pili to mediate host colonization, including the type IVb pilus, colonization factor antigen III (CFA/III). Not all colonization factors are well characterized or known in toxin positive ETEC isolates, which may have an imp...

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Autores principales: Njoroge, Samuel M., Boinett, Christine J., Madé, Laure F., Ouko, Tom T., Fèvre, Eric M., Thomson, Nicholas R., Kariuki, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Shortomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535451/
https://www.ncbi.nlm.nih.gov/pubmed/26187892
http://dx.doi.org/10.1093/femspd/ftv047
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author Njoroge, Samuel M.
Boinett, Christine J.
Madé, Laure F.
Ouko, Tom T.
Fèvre, Eric M.
Thomson, Nicholas R.
Kariuki, Samuel
author_facet Njoroge, Samuel M.
Boinett, Christine J.
Madé, Laure F.
Ouko, Tom T.
Fèvre, Eric M.
Thomson, Nicholas R.
Kariuki, Samuel
author_sort Njoroge, Samuel M.
collection PubMed
description Enterotoxigenic Escherichia coli (ETEC) strains harbor multiple fimbriae and pili to mediate host colonization, including the type IVb pilus, colonization factor antigen III (CFA/III). Not all colonization factors are well characterized or known in toxin positive ETEC isolates, which may have an impact identifying ETEC isolates based on molecular screening of these biomarkers. We describe a novel coli surface antigen (CS) 8 subtype B (CS8B), a family of CFA/III pilus, in a toxin producing ETEC isolate from a Kenyan collection. In highlighting the existence of this putative CS, we provide the sequence and specific primers, which can be used alongside other ETEC primers previously described.
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spelling pubmed-45354512015-08-17 A putative, novel coli surface antigen 8B (CS8B) of enterotoxigenic Escherichia coli Njoroge, Samuel M. Boinett, Christine J. Madé, Laure F. Ouko, Tom T. Fèvre, Eric M. Thomson, Nicholas R. Kariuki, Samuel Pathog Dis Shortomics Enterotoxigenic Escherichia coli (ETEC) strains harbor multiple fimbriae and pili to mediate host colonization, including the type IVb pilus, colonization factor antigen III (CFA/III). Not all colonization factors are well characterized or known in toxin positive ETEC isolates, which may have an impact identifying ETEC isolates based on molecular screening of these biomarkers. We describe a novel coli surface antigen (CS) 8 subtype B (CS8B), a family of CFA/III pilus, in a toxin producing ETEC isolate from a Kenyan collection. In highlighting the existence of this putative CS, we provide the sequence and specific primers, which can be used alongside other ETEC primers previously described. Oxford University Press 2015-07-17 2015-10 /pmc/articles/PMC4535451/ /pubmed/26187892 http://dx.doi.org/10.1093/femspd/ftv047 Text en © FEMS 2015. http://creativecommons.org/licenses/by/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Shortomics
Njoroge, Samuel M.
Boinett, Christine J.
Madé, Laure F.
Ouko, Tom T.
Fèvre, Eric M.
Thomson, Nicholas R.
Kariuki, Samuel
A putative, novel coli surface antigen 8B (CS8B) of enterotoxigenic Escherichia coli
title A putative, novel coli surface antigen 8B (CS8B) of enterotoxigenic Escherichia coli
title_full A putative, novel coli surface antigen 8B (CS8B) of enterotoxigenic Escherichia coli
title_fullStr A putative, novel coli surface antigen 8B (CS8B) of enterotoxigenic Escherichia coli
title_full_unstemmed A putative, novel coli surface antigen 8B (CS8B) of enterotoxigenic Escherichia coli
title_short A putative, novel coli surface antigen 8B (CS8B) of enterotoxigenic Escherichia coli
title_sort putative, novel coli surface antigen 8b (cs8b) of enterotoxigenic escherichia coli
topic Shortomics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535451/
https://www.ncbi.nlm.nih.gov/pubmed/26187892
http://dx.doi.org/10.1093/femspd/ftv047
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