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Genome-wide binding of transcription factors in inv(16) acute myeloid leukemia
The inv(16) translocation is associated with 5% of AML cases and gives rise to expression of the oncofusion protein CBFβ-MYH11. Although different molecular mechanisms for the oncogenic activity of this fusion protein have been proposed these were mostly based on in vitro experiments or single loci...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535528/ https://www.ncbi.nlm.nih.gov/pubmed/26484088 http://dx.doi.org/10.1016/j.gdata.2014.06.014 |