Returning to more finished genomes

Genomic data have become commonplace in most branches of the biological sciences and have fundamentally altered the way research is conducted. However, the predominance of short-read sequence data from second-generation sequencing technologies has commonly resulted in fragmented and partial genomic...

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Detalles Bibliográficos
Autor principal: Korlach, Jonas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Special Section “Democratizing Genomics Data”
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535613/
https://www.ncbi.nlm.nih.gov/pubmed/26484068
http://dx.doi.org/10.1016/j.gdata.2014.02.003
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author Korlach, Jonas
author_facet Korlach, Jonas
author_sort Korlach, Jonas
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description Genomic data have become commonplace in most branches of the biological sciences and have fundamentally altered the way research is conducted. However, the predominance of short-read sequence data from second-generation sequencing technologies has commonly resulted in fragmented and partial genomic data characteristics. In this opinion, I will highlight how long, unbiased reads from single molecule, real-time (SMRT) sequencing now allow for a return to more contiguous and comprehensive views of genomes.
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spelling pubmed-45356132015-10-19 Returning to more finished genomes Korlach, Jonas Genom Data Special Section “Democratizing Genomics Data” Genomic data have become commonplace in most branches of the biological sciences and have fundamentally altered the way research is conducted. However, the predominance of short-read sequence data from second-generation sequencing technologies has commonly resulted in fragmented and partial genomic data characteristics. In this opinion, I will highlight how long, unbiased reads from single molecule, real-time (SMRT) sequencing now allow for a return to more contiguous and comprehensive views of genomes. Elsevier 2014-03-01 /pmc/articles/PMC4535613/ /pubmed/26484068 http://dx.doi.org/10.1016/j.gdata.2014.02.003 Text en © 2014 The Authors http://creativecommons.org/licenses/by/3.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Special Section “Democratizing Genomics Data”
Korlach, Jonas
Returning to more finished genomes
title Returning to more finished genomes
title_full Returning to more finished genomes
title_fullStr Returning to more finished genomes
title_full_unstemmed Returning to more finished genomes
title_short Returning to more finished genomes
title_sort returning to more finished genomes
topic Special Section “Democratizing Genomics Data”
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535613/
https://www.ncbi.nlm.nih.gov/pubmed/26484068
http://dx.doi.org/10.1016/j.gdata.2014.02.003
work_keys_str_mv AT korlachjonas returningtomorefinishedgenomes

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