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Post-Operative Complications in Living Liver Donors: A Single-Center Experience in China

The gap between the growing demand for available organs and the cadaveric organs facilitates the adoption of living donor liver transplantation. We retrospectively identified and evaluated the post-operative complications as per the modified Clavien classification system in 152 living liver donors a...

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Autores principales: Sun, Zhongquan, Yu, Zhiyong, Yu, Songfeng, Chen, Jihao, Wang, Jingqiao, Yang, Cheng, Jin, Mengmeng, Yan, Sheng, Zhang, Mangli, Zhang, Min, Zheng, Shusen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535761/
https://www.ncbi.nlm.nih.gov/pubmed/26270475
http://dx.doi.org/10.1371/journal.pone.0135557
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author Sun, Zhongquan
Yu, Zhiyong
Yu, Songfeng
Chen, Jihao
Wang, Jingqiao
Yang, Cheng
Jin, Mengmeng
Yan, Sheng
Zhang, Mangli
Zhang, Min
Zheng, Shusen
author_facet Sun, Zhongquan
Yu, Zhiyong
Yu, Songfeng
Chen, Jihao
Wang, Jingqiao
Yang, Cheng
Jin, Mengmeng
Yan, Sheng
Zhang, Mangli
Zhang, Min
Zheng, Shusen
author_sort Sun, Zhongquan
collection PubMed
description The gap between the growing demand for available organs and the cadaveric organs facilitates the adoption of living donor liver transplantation. We retrospectively identified and evaluated the post-operative complications as per the modified Clavien classification system in 152 living liver donors at at the First Affiliated Hospital, College of Medicine, Zhejiang University between December, 2006 and June, 2014. Post-operative complications were observed in 61 patients (40.1%) in the present study, but no mortality was reported. Complications developed in 58 (40.0%) right, 1 (33.3%) left, and 2 (66.7%) lateral left hepatectomy donors. The prevalence of re-operation was 1.3%. Grade I and II complications were observed in 38 (25.0%) and 11 (7.2%) donors, respectively. Grade IIIa complications developed in 9 (5.9%) donors and only 3 (2.0%) patients reported grade IIIb complications. The most common complication was pleural effusion that occurred in 31 (20.4%) donors. No significant prognostic baseline factor was identified in this study. In conclusion, living donors experienced various complications, which were usually mild and had a good prognosis.
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spelling pubmed-45357612015-08-20 Post-Operative Complications in Living Liver Donors: A Single-Center Experience in China Sun, Zhongquan Yu, Zhiyong Yu, Songfeng Chen, Jihao Wang, Jingqiao Yang, Cheng Jin, Mengmeng Yan, Sheng Zhang, Mangli Zhang, Min Zheng, Shusen PLoS One Research Article The gap between the growing demand for available organs and the cadaveric organs facilitates the adoption of living donor liver transplantation. We retrospectively identified and evaluated the post-operative complications as per the modified Clavien classification system in 152 living liver donors at at the First Affiliated Hospital, College of Medicine, Zhejiang University between December, 2006 and June, 2014. Post-operative complications were observed in 61 patients (40.1%) in the present study, but no mortality was reported. Complications developed in 58 (40.0%) right, 1 (33.3%) left, and 2 (66.7%) lateral left hepatectomy donors. The prevalence of re-operation was 1.3%. Grade I and II complications were observed in 38 (25.0%) and 11 (7.2%) donors, respectively. Grade IIIa complications developed in 9 (5.9%) donors and only 3 (2.0%) patients reported grade IIIb complications. The most common complication was pleural effusion that occurred in 31 (20.4%) donors. No significant prognostic baseline factor was identified in this study. In conclusion, living donors experienced various complications, which were usually mild and had a good prognosis. Public Library of Science 2015-08-13 /pmc/articles/PMC4535761/ /pubmed/26270475 http://dx.doi.org/10.1371/journal.pone.0135557 Text en © 2015 Sun et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Sun, Zhongquan
Yu, Zhiyong
Yu, Songfeng
Chen, Jihao
Wang, Jingqiao
Yang, Cheng
Jin, Mengmeng
Yan, Sheng
Zhang, Mangli
Zhang, Min
Zheng, Shusen
Post-Operative Complications in Living Liver Donors: A Single-Center Experience in China
title Post-Operative Complications in Living Liver Donors: A Single-Center Experience in China
title_full Post-Operative Complications in Living Liver Donors: A Single-Center Experience in China
title_fullStr Post-Operative Complications in Living Liver Donors: A Single-Center Experience in China
title_full_unstemmed Post-Operative Complications in Living Liver Donors: A Single-Center Experience in China
title_short Post-Operative Complications in Living Liver Donors: A Single-Center Experience in China
title_sort post-operative complications in living liver donors: a single-center experience in china
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535761/
https://www.ncbi.nlm.nih.gov/pubmed/26270475
http://dx.doi.org/10.1371/journal.pone.0135557
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