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Apoptosis induction by combination of drugs or a conjugated molecule associating non-steroidal anti-inflammatory and nitric oxide donor effects in medullary thyroid cancer models: implication of the tumor suppressor p73

BACKGROUND: Medullary thyroid cancer (MTC) is a C-cell neoplasm. Surgery remains its main treatment. Promising therapies based on tyrosine kinase inhibitors demand careful patient selection. We previously observed that two non-steroidal anti-inflammatory drugs (NSAID), indomethacin, celecoxib, and n...

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Detalles Bibliográficos
Autores principales: Ragot, Thierry, Provost, Claire, Prignon, Aurélie, Cohen, Régis, Lepoivre, Michel, Lausson, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535850/
https://www.ncbi.nlm.nih.gov/pubmed/26273323
http://dx.doi.org/10.1186/s13044-015-0025-3

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