Multipotent human stromal cells isolated from cord blood, term placenta and adult bone marrow show distinct differences in gene expression pattern

Multipotent mesenchymal stromal cells derived from human placenta (pMSCs), and unrestricted somatic stem cells (USSCs) derived from cord blood share many properties with human bone marrow-derived mesenchymal stromal cells (bmMSCs) and are currently in clinical trials for a wide range of clinical set...

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Autores principales: Matigian, Nicholas, Brooke, Gary, Zaibak, Faten, Rossetti, Tony, Kollar, Katarina, Pelekanos, Rebecca, Heazlewood, Celena, Mackay-Sim, Alan, Wells, Christine A., Atkinson, Kerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Data in Brief
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535874/
https://www.ncbi.nlm.nih.gov/pubmed/26484151
http://dx.doi.org/10.1016/j.gdata.2014.11.011
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author Matigian, Nicholas
Brooke, Gary
Zaibak, Faten
Rossetti, Tony
Kollar, Katarina
Pelekanos, Rebecca
Heazlewood, Celena
Mackay-Sim, Alan
Wells, Christine A.
Atkinson, Kerry
author_facet Matigian, Nicholas
Brooke, Gary
Zaibak, Faten
Rossetti, Tony
Kollar, Katarina
Pelekanos, Rebecca
Heazlewood, Celena
Mackay-Sim, Alan
Wells, Christine A.
Atkinson, Kerry
author_sort Matigian, Nicholas
collection PubMed
description Multipotent mesenchymal stromal cells derived from human placenta (pMSCs), and unrestricted somatic stem cells (USSCs) derived from cord blood share many properties with human bone marrow-derived mesenchymal stromal cells (bmMSCs) and are currently in clinical trials for a wide range of clinical settings. Here we present gene expression profiles of human cord blood-derived unrestricted somatic stem cells (USSCs), human placental-derived mesenchymal stem cells (hpMSCs), and human bone marrow-derived mesenchymal stromal cells (bmMSCs), all derived from four different donors. The microarray data are available on the ArrayExpress database (www.ebi.ac.uk/arrayexpress) under accession number E-TABM-880. Additionally, the data has been integrated into a public portal, www.stemformatics.org. Our data provide a resource for understanding the differences in MSCs derived from different tissues.
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spelling pubmed-45358742015-10-19 Multipotent human stromal cells isolated from cord blood, term placenta and adult bone marrow show distinct differences in gene expression pattern Matigian, Nicholas Brooke, Gary Zaibak, Faten Rossetti, Tony Kollar, Katarina Pelekanos, Rebecca Heazlewood, Celena Mackay-Sim, Alan Wells, Christine A. Atkinson, Kerry Genom Data Data in Brief Multipotent mesenchymal stromal cells derived from human placenta (pMSCs), and unrestricted somatic stem cells (USSCs) derived from cord blood share many properties with human bone marrow-derived mesenchymal stromal cells (bmMSCs) and are currently in clinical trials for a wide range of clinical settings. Here we present gene expression profiles of human cord blood-derived unrestricted somatic stem cells (USSCs), human placental-derived mesenchymal stem cells (hpMSCs), and human bone marrow-derived mesenchymal stromal cells (bmMSCs), all derived from four different donors. The microarray data are available on the ArrayExpress database (www.ebi.ac.uk/arrayexpress) under accession number E-TABM-880. Additionally, the data has been integrated into a public portal, www.stemformatics.org. Our data provide a resource for understanding the differences in MSCs derived from different tissues. Elsevier 2014-11-28 /pmc/articles/PMC4535874/ /pubmed/26484151 http://dx.doi.org/10.1016/j.gdata.2014.11.011 Text en © 2014 The Authors http://creativecommons.org/licenses/by/3.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Data in Brief
Matigian, Nicholas
Brooke, Gary
Zaibak, Faten
Rossetti, Tony
Kollar, Katarina
Pelekanos, Rebecca
Heazlewood, Celena
Mackay-Sim, Alan
Wells, Christine A.
Atkinson, Kerry
Multipotent human stromal cells isolated from cord blood, term placenta and adult bone marrow show distinct differences in gene expression pattern
title Multipotent human stromal cells isolated from cord blood, term placenta and adult bone marrow show distinct differences in gene expression pattern
title_full Multipotent human stromal cells isolated from cord blood, term placenta and adult bone marrow show distinct differences in gene expression pattern
title_fullStr Multipotent human stromal cells isolated from cord blood, term placenta and adult bone marrow show distinct differences in gene expression pattern
title_full_unstemmed Multipotent human stromal cells isolated from cord blood, term placenta and adult bone marrow show distinct differences in gene expression pattern
title_short Multipotent human stromal cells isolated from cord blood, term placenta and adult bone marrow show distinct differences in gene expression pattern
title_sort multipotent human stromal cells isolated from cord blood, term placenta and adult bone marrow show distinct differences in gene expression pattern
topic Data in Brief
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535874/
https://www.ncbi.nlm.nih.gov/pubmed/26484151
http://dx.doi.org/10.1016/j.gdata.2014.11.011
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