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How Heme Oxygenase-1 Prevents Heme-Induced Cell Death
Earlier observations indicate that free heme is selectively toxic to cells lacking heme oxygenase-1 (HO-1) but how this enzyme prevents heme toxicity remains unexplained. Here, using A549 (human lung cancer) and immortalized human bronchial epithelial cells incubated with exogenous heme, we find kno...
Autores principales: | Lanceta, Lilibeth, Mattingly, Jacob M., Li, Chi, Eaton, John W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535878/ https://www.ncbi.nlm.nih.gov/pubmed/26270345 http://dx.doi.org/10.1371/journal.pone.0134144 |
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