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A Single-Strand Annealing Protein Clamps DNA to Detect and Secure Homology

Repair of DNA breaks by single-strand annealing (SSA) is a major mechanism for the maintenance of genomic integrity. SSA is promoted by proteins (single-strand-annealing proteins [SSAPs]), such as eukaryotic RAD52 and λ phage Redβ. These proteins use a short single-stranded region to find sequence i...

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Detalles Bibliográficos
Autores principales: Ander, Marcel, Subramaniam, Sivaraman, Fahmy, Karim, Stewart, A. Francis, Schäffer, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535883/
https://www.ncbi.nlm.nih.gov/pubmed/26271032
http://dx.doi.org/10.1371/journal.pbio.1002213

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