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Destabilizing DNA during Rejoining Enhances Fidelity of Repair
A new study shows that during repair of DNA, the effect of a single-strand annealing protein is to destabilize DNA duplex formation so that annealing only occurs between perfectly matched strands; the protein then clamps the strands together for repair. Read the Research Article.
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535887/ https://www.ncbi.nlm.nih.gov/pubmed/26271078 http://dx.doi.org/10.1371/journal.pbio.1002214 |