A definitive haplotype map of structural variations determined by microarray analysis of duplicated haploid genomes

Complete hydatidiform moles (CHMs) are tissues carrying duplicated haploid genomes derived from single sperms, and detecting copy number variations (CNVs) in CHMs is assumed to be sensitive and straightforward methods. We genotyped 108 CHM genomes using Affymetrix SNP 6.0 (GEO#: GSE18642) and Illumi...

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Autores principales: Tahira, Tomoko, Yahara, Koji, Kukita, Yoji, Higasa, Koichiro, Kato, Kiyoko, Wake, Norio, Hayashi, Kenshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Data in Brief
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535890/
https://www.ncbi.nlm.nih.gov/pubmed/26484070
http://dx.doi.org/10.1016/j.gdata.2014.04.006
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author Tahira, Tomoko
Yahara, Koji
Kukita, Yoji
Higasa, Koichiro
Kato, Kiyoko
Wake, Norio
Hayashi, Kenshi
author_facet Tahira, Tomoko
Yahara, Koji
Kukita, Yoji
Higasa, Koichiro
Kato, Kiyoko
Wake, Norio
Hayashi, Kenshi
author_sort Tahira, Tomoko
collection PubMed
description Complete hydatidiform moles (CHMs) are tissues carrying duplicated haploid genomes derived from single sperms, and detecting copy number variations (CNVs) in CHMs is assumed to be sensitive and straightforward methods. We genotyped 108 CHM genomes using Affymetrix SNP 6.0 (GEO#: GSE18642) and Illumina 1 M-duo (GEO#: GSE54948). After quality control, we obtained 84 definitive haplotype consisting of 1.7 million SNPs and 2339 CNV regions. The results are presented in the database of our web site (http://orca.gen.kyushu-u.ac.jp/cgi-bin/gbrowse/humanBuild37D4_1/).
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spelling pubmed-45358902015-10-19 A definitive haplotype map of structural variations determined by microarray analysis of duplicated haploid genomes Tahira, Tomoko Yahara, Koji Kukita, Yoji Higasa, Koichiro Kato, Kiyoko Wake, Norio Hayashi, Kenshi Genom Data Data in Brief Complete hydatidiform moles (CHMs) are tissues carrying duplicated haploid genomes derived from single sperms, and detecting copy number variations (CNVs) in CHMs is assumed to be sensitive and straightforward methods. We genotyped 108 CHM genomes using Affymetrix SNP 6.0 (GEO#: GSE18642) and Illumina 1 M-duo (GEO#: GSE54948). After quality control, we obtained 84 definitive haplotype consisting of 1.7 million SNPs and 2339 CNV regions. The results are presented in the database of our web site (http://orca.gen.kyushu-u.ac.jp/cgi-bin/gbrowse/humanBuild37D4_1/). Elsevier 2014-04-24 /pmc/articles/PMC4535890/ /pubmed/26484070 http://dx.doi.org/10.1016/j.gdata.2014.04.006 Text en © 2014 The Authors http://creativecommons.org/licenses/by/3.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Data in Brief
Tahira, Tomoko
Yahara, Koji
Kukita, Yoji
Higasa, Koichiro
Kato, Kiyoko
Wake, Norio
Hayashi, Kenshi
A definitive haplotype map of structural variations determined by microarray analysis of duplicated haploid genomes
title A definitive haplotype map of structural variations determined by microarray analysis of duplicated haploid genomes
title_full A definitive haplotype map of structural variations determined by microarray analysis of duplicated haploid genomes
title_fullStr A definitive haplotype map of structural variations determined by microarray analysis of duplicated haploid genomes
title_full_unstemmed A definitive haplotype map of structural variations determined by microarray analysis of duplicated haploid genomes
title_short A definitive haplotype map of structural variations determined by microarray analysis of duplicated haploid genomes
title_sort definitive haplotype map of structural variations determined by microarray analysis of duplicated haploid genomes
topic Data in Brief
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535890/
https://www.ncbi.nlm.nih.gov/pubmed/26484070
http://dx.doi.org/10.1016/j.gdata.2014.04.006
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