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The Expression of the Zonula Adhaerens Protein PLEKHA7 Is Strongly Decreased in High Grade Ductal and Lobular Breast Carcinomas
PLEKHA7 is a junctional protein, which participates in a complex that stabilizes E-cadherin at the zonula adhaerens. Since E-cadherin is involved in epithelial morphogenesis, signaling, and tumor progression, we explored PLEKHA7 expression in cancer. PLEKHA7 expression was assessed in invasive ducta...
Autores principales: | Tille, Jean-Christophe, Ho, Liza, Shah, Jimit, Seyde, Olivia, McKee, Thomas A., Citi, Sandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535953/ https://www.ncbi.nlm.nih.gov/pubmed/26270346 http://dx.doi.org/10.1371/journal.pone.0135442 |
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