Human miRNome profiling in colorectal cancer and liver metastasis development

Qualitative alterations or abnormal expression of microRNAs (miRNAs) in colorectal cancer has mainly been demonstrated in primary tumors. The miRNA expression profiles in 78 samples from 46 patients were analyzed to identify changes in miRNA expression level among normal colon mucosa, primary tumor...

Descripción completa

Detalles Bibliográficos
Autores principales: Perilli, Lisa, Pizzini, Silvia, Bisognin, Andrea, Mandruzzato, Susanna, Biasiolo, Marta, Facciolli, Arianna, Rossi, Elisabetta, Esposito, Giovanni, Rugge, Massimo, Pilati, Pierluigi, Mocellin, Simone, Nitti, Donato, Bortoluzzi, Stefania, Zanovello, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Data in Brief
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535971/
https://www.ncbi.nlm.nih.gov/pubmed/26484092
http://dx.doi.org/10.1016/j.gdata.2014.06.017
Descripción
Sumario:Qualitative alterations or abnormal expression of microRNAs (miRNAs) in colorectal cancer has mainly been demonstrated in primary tumors. The miRNA expression profiles in 78 samples from 46 patients were analyzed to identify changes in miRNA expression level among normal colon mucosa, primary tumor and liver metastasis samples. Using this dataset, we describe the interplay of miRNA groups in regulating pathways that are important for tumor development. Here we describe in details the contents and quality controls for the miRNA expression and clinical data associated with the study published by Pizzini and colleagues in the BMC Genomics in 2013 (Pizzini et al., 2013). Data are deposited in GEO database as GSE35834 series.

Ejemplares similares