Cargando…
Human miRNome profiling in colorectal cancer and liver metastasis development
Qualitative alterations or abnormal expression of microRNAs (miRNAs) in colorectal cancer has mainly been demonstrated in primary tumors. The miRNA expression profiles in 78 samples from 46 patients were analyzed to identify changes in miRNA expression level among normal colon mucosa, primary tumor...
| Autores principales: | , , , , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535971/ https://www.ncbi.nlm.nih.gov/pubmed/26484092 http://dx.doi.org/10.1016/j.gdata.2014.06.017 |
| _version_ | 1782385680434855936 |
|---|---|
| author | Perilli, Lisa Pizzini, Silvia Bisognin, Andrea Mandruzzato, Susanna Biasiolo, Marta Facciolli, Arianna Rossi, Elisabetta Esposito, Giovanni Rugge, Massimo Pilati, Pierluigi Mocellin, Simone Nitti, Donato Bortoluzzi, Stefania Zanovello, Paola |
| author_facet | Perilli, Lisa Pizzini, Silvia Bisognin, Andrea Mandruzzato, Susanna Biasiolo, Marta Facciolli, Arianna Rossi, Elisabetta Esposito, Giovanni Rugge, Massimo Pilati, Pierluigi Mocellin, Simone Nitti, Donato Bortoluzzi, Stefania Zanovello, Paola |
| author_sort | Perilli, Lisa |
| collection | PubMed |
| description | Qualitative alterations or abnormal expression of microRNAs (miRNAs) in colorectal cancer has mainly been demonstrated in primary tumors. The miRNA expression profiles in 78 samples from 46 patients were analyzed to identify changes in miRNA expression level among normal colon mucosa, primary tumor and liver metastasis samples. Using this dataset, we describe the interplay of miRNA groups in regulating pathways that are important for tumor development. Here we describe in details the contents and quality controls for the miRNA expression and clinical data associated with the study published by Pizzini and colleagues in the BMC Genomics in 2013 (Pizzini et al., 2013). Data are deposited in GEO database as GSE35834 series. |
| format | Online Article Text |
| id | pubmed-4535971 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2014 |
| publisher | Elsevier |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-45359712015-10-19 Human miRNome profiling in colorectal cancer and liver metastasis development Perilli, Lisa Pizzini, Silvia Bisognin, Andrea Mandruzzato, Susanna Biasiolo, Marta Facciolli, Arianna Rossi, Elisabetta Esposito, Giovanni Rugge, Massimo Pilati, Pierluigi Mocellin, Simone Nitti, Donato Bortoluzzi, Stefania Zanovello, Paola Genom Data Data in Brief Qualitative alterations or abnormal expression of microRNAs (miRNAs) in colorectal cancer has mainly been demonstrated in primary tumors. The miRNA expression profiles in 78 samples from 46 patients were analyzed to identify changes in miRNA expression level among normal colon mucosa, primary tumor and liver metastasis samples. Using this dataset, we describe the interplay of miRNA groups in regulating pathways that are important for tumor development. Here we describe in details the contents and quality controls for the miRNA expression and clinical data associated with the study published by Pizzini and colleagues in the BMC Genomics in 2013 (Pizzini et al., 2013). Data are deposited in GEO database as GSE35834 series. Elsevier 2014-06-27 /pmc/articles/PMC4535971/ /pubmed/26484092 http://dx.doi.org/10.1016/j.gdata.2014.06.017 Text en © 2014 The Authors http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/). |
| spellingShingle | Data in Brief Perilli, Lisa Pizzini, Silvia Bisognin, Andrea Mandruzzato, Susanna Biasiolo, Marta Facciolli, Arianna Rossi, Elisabetta Esposito, Giovanni Rugge, Massimo Pilati, Pierluigi Mocellin, Simone Nitti, Donato Bortoluzzi, Stefania Zanovello, Paola Human miRNome profiling in colorectal cancer and liver metastasis development |
| title | Human miRNome profiling in colorectal cancer and liver metastasis development |
| title_full | Human miRNome profiling in colorectal cancer and liver metastasis development |
| title_fullStr | Human miRNome profiling in colorectal cancer and liver metastasis development |
| title_full_unstemmed | Human miRNome profiling in colorectal cancer and liver metastasis development |
| title_short | Human miRNome profiling in colorectal cancer and liver metastasis development |
| title_sort | human mirnome profiling in colorectal cancer and liver metastasis development |
| topic | Data in Brief |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535971/ https://www.ncbi.nlm.nih.gov/pubmed/26484092 http://dx.doi.org/10.1016/j.gdata.2014.06.017 |
| work_keys_str_mv | AT perillilisa humanmirnomeprofilingincolorectalcancerandlivermetastasisdevelopment AT pizzinisilvia humanmirnomeprofilingincolorectalcancerandlivermetastasisdevelopment AT bisogninandrea humanmirnomeprofilingincolorectalcancerandlivermetastasisdevelopment AT mandruzzatosusanna humanmirnomeprofilingincolorectalcancerandlivermetastasisdevelopment AT biasiolomarta humanmirnomeprofilingincolorectalcancerandlivermetastasisdevelopment AT facciolliarianna humanmirnomeprofilingincolorectalcancerandlivermetastasisdevelopment AT rossielisabetta humanmirnomeprofilingincolorectalcancerandlivermetastasisdevelopment AT espositogiovanni humanmirnomeprofilingincolorectalcancerandlivermetastasisdevelopment AT ruggemassimo humanmirnomeprofilingincolorectalcancerandlivermetastasisdevelopment AT pilatipierluigi humanmirnomeprofilingincolorectalcancerandlivermetastasisdevelopment AT mocellinsimone humanmirnomeprofilingincolorectalcancerandlivermetastasisdevelopment AT nittidonato humanmirnomeprofilingincolorectalcancerandlivermetastasisdevelopment AT bortoluzzistefania humanmirnomeprofilingincolorectalcancerandlivermetastasisdevelopment AT zanovellopaola humanmirnomeprofilingincolorectalcancerandlivermetastasisdevelopment |