Cargando…

How Can We Improve the Detection of Alpha1-Antitrypsin Deficiency?

The Z deficiency in α1-antitrypsin (A1ATD) is an under-recognized condition. Alpha1-antitrypsin (A1AT) is the main protein in the α1-globulin fraction of serum protein electrophoresis (SPE); however, evaluation of the α1-globulin protein fraction has received very little attention. Serum Z-type A1AT...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ferrarotti, Ilaria, Poplawska-Wisniewska, Beata, Trevisan, Maria Teresa, Koepke, Janine, Dresel, Marc, Koczulla, Rembert, Ottaviani, Stefania, Baldo, Raffaele, Gorrini, Marina, Sala, Giorgia, Cavallon, Luana, Welte, Tobias, Chorostowska-Wynimko, Joanna, Luisetti, Maurizio, Janciauskiene, Sabina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536179/ https://www.ncbi.nlm.nih.gov/pubmed/26270547 http://dx.doi.org/10.1371/journal.pone.0135316

Ejemplares similares

Alpha 1 antitrypsin to treat lung disease in alpha 1 antitrypsin deficiency: recent developments and clinical implications
por: Chapman, Kenneth R, et al.
Publicado: (2018)

The Multifaceted Effects of Alpha1-Antitrypsin on Neutrophil Functions
por: Janciauskiene, Sabina, et al.
Publicado: (2018)

Does Augmentation with Alpha1-Antitrypsin Affect Neutrophil Extracellular Traps Formation?
por: Frenzel, Eileen, et al.
Publicado: (2012)

Therapy with Plasma Purified Alpha1-Antitrypsin (Prolastin(®)) Induces Time-Dependent Changes in Plasma Levels of MMP-9 and MPO
por: Koepke, Janine, et al.
Publicado: (2015)

Post-Translational Modifications of Circulating Alpha-1-Antitrypsin Protein
por: Lechowicz, Urszula, et al.
Publicado: (2020)

Krüppel-like zinc finger proteins in end-stage COPD lungs with and without severe alpha1-antitrypsin deficiency
por: Koczulla, A-Rembert, et al.
Publicado: (2012)

Does urinary peptide content differ between COPD patients with and without inherited alpha-1 antitrypsin deficiency?
por: Carleo, Alfonso, et al.
Publicado: (2017)

New Patient-Centric Approaches to the Management of Alpha-1 Antitrypsin Deficiency
por: Chorostowska-Wynimko, Joanna, et al.
Publicado: (2020)

Targeted screening programmes in COPD: how to identify individuals with α(1)-antitrypsin deficiency
por: Chorostowska-Wynimko, Joanna
Publicado: (2015)

The effects of weekly augmentation therapy in patients with PiZZ α1-antitrypsin deficiency
por: Schmid, ST, et al.
Publicado: (2012)

Screening for Alpha 1 antitrypsin deficiency in Tunisian subjects with obstructive lung disease: a feasibility report
por: Denden, Sabri, et al.
Publicado: (2009)

α(1)-antitrypsin modulates microglial-mediated neuroinflammation and protects microglial cells from amyloid-β-induced toxicity
por: Gold, Maike, et al.
Publicado: (2014)

The Relationship between Plasma Alpha-1-Antitrypsin Polymers and Lung or Liver Function in ZZ Alpha-1-Antitrypsin-Deficient Patients
por: Sark, Annelot D., et al.
Publicado: (2022)

SERPINA1 and More? A Putative Genetic Contributor to Pulmonary Dysfunction in Alpha-1 Antitrypsin Deficiency
por: Jezela-Stanek, Aleksandra, et al.
Publicado: (2023)

The Distribution of Alpha-1 Antitrypsin Genotypes Between Patients with COPD/Emphysema, Asthma and Bronchiectasis
por: Veith, Martina, et al.
Publicado: (2020)

The role of bronchial epithelial cells in the pathogenesis of COPD in Z-alpha-1 antitrypsin deficiency
por: Pini, Laura, et al.
Publicado: (2014)

Molecular diagnosis of alpha1‐antitrypsin deficiency: A new method based on Luminex technology
por: Ottaviani, Stefania, et al.
Publicado: (2020)

Update on α(1)-antitrypsin deficiency
por: Ferrarotti, Ilaria, et al.
Publicado: (2018)

Case-finding for alpha1-antitrypsin deficiency in Kazakh patients with COPD
por: Zhumagaliyeva, Ardak, et al.
Publicado: (2017)

Research priorities in α(1)-antitrypsin deficiency: results of a patients' and healthcare providers' international survey from the EARCO Clinical Research Collaboration
por: Barrecheguren, Miriam, et al.
Publicado: (2020)

Acute Phase Proteins as Early Predictors for Immunotherapy Response in Advanced NSCLC: An Explorative Study
por: Schneider, Marc A., et al.
Publicado: (2022)

Improving the Lives of Patients with Alpha-1 Antitrypsin Deficiency
por: Sandhaus, Robert A, et al.
Publicado: (2020)

Alternative transcripts of the SERPINA1 gene in alpha-1 antitrypsin deficiency
por: Matamala, Nerea, et al.
Publicado: (2015)

Benefits of whole body vibration training in patients hospitalised for COPD exacerbations - a randomized clinical trial
por: Greulich, Timm, et al.
Publicado: (2014)

A Novel Mouse Monoclonal Antibody C42 against C-Terminal Peptide of Alpha-1-Antitrypsin
por: Tumpara, Srinu, et al.
Publicado: (2021)

Alpha1-antitrypsin protects lung cancer cells from staurosporine-induced apoptosis: the role of bacterial lipopolysaccharide
por: Schwarz, Natalie, et al.
Publicado: (2020)

Plasma Acute Phase Proteins as Predictors of Chronic Lung Allograft Dysfunction in Lung Transplant Recipients
por: Janciauskiene, Sabina, et al.
Publicado: (2020)

Indirect effect of alpha-1-antitrypsin on endotoxin-induced IL-1β secretion from human PBMCs
por: Janciauskiene, Sabina, et al.
Publicado: (2022)

SP-A binds alpha(1)-antitrypsin in vitro and reduces the association rate constant for neutrophil elastase
por: Gorrini, Marina, et al.
Publicado: (2005)

Alpha-1 antitrypsin deficiency impairs lung antibacterial immunity in mice
por: Ostermann, Lena, et al.
Publicado: (2021)

Why do some adults with PiMZ α(1)-antitrypsin develop bronchiectasis?
por: Aggarwal, Nupur, et al.
Publicado: (2016)

Potential Roles of Acute Phase Proteins in Cancer: Why Do Cancer Cells Produce or Take Up Exogenous Acute Phase Protein Alpha1-Antitrypsin?
por: Janciauskiene, Sabina, et al.
Publicado: (2021)

Cardiovascular risk in patients with alpha-1-antitrypsin deficiency
por: Fähndrich, Sebastian, et al.
Publicado: (2017)

α1-Antitrypsin attenuates acute rejection of orthotopic murine lung allografts
por: Nakagiri, Tomoyuki, et al.
Publicado: (2021)

Concentration-dependent effects of native and polymerised α1-antitrypsin on primary human monocytes, in vitro
por: Aldonyte, Ruta, et al.
Publicado: (2004)

Boosted Pro-Inflammatory Activity in Human PBMCs by Lipopolysaccharide and SARS-CoV-2 Spike Protein Is Regulated by α-1 Antitrypsin †
por: Tumpara, Srinu, et al.
Publicado: (2021)

Alpha-1 Antitrypsin Z Variant (AAT PI*Z) as a Risk Factor for Intrahepatic Cholestasis of Pregnancy
por: Kosinski, Przemyslaw, et al.
Publicado: (2021)

Protocol for the EARCO Registry: a pan-European observational study in patients with α(1)-antitrypsin deficiency
por: Greulich, Timm, et al.
Publicado: (2020)

Beneficial effects of alpha-1 antitrypsin therapy in a mouse model of colitis-associated colon cancer
por: Al-Omari, Mariam, et al.
Publicado: (2023)

COVID-19 infection in severe Alpha 1-antitrypsin deficiency: Looking for a rationale
por: Ferrarotti, I., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_thfr13jc8kndbhvrlti0j7aial