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Promoter Methylation Status Modulate the Expression of Tumor Suppressor (RbL2/p130) Gene in Breast Cancer

BACKGROUND: Aberrant expression of tumor suppressor genes may correspond to the abnormal cell development and tumorigenesis. Rbl2/p130, a member of retinoblastoma family of proteins, has growth suppressive properties. Numerous studies reported de-regulation of Rbl2/p130 in various types of cancer as...

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Detalles Bibliográficos
Autores principales: Ullah, Farman, Khan, Taimoor, Ali, Nawab, Malik, Faraz Arshad, Kayani, Mahmood Akhtar, Shah, Syed Tahir Abbas, Saeed, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536218/
https://www.ncbi.nlm.nih.gov/pubmed/26271034
http://dx.doi.org/10.1371/journal.pone.0134687