Disabling amnestic syndrome following stereotactic laser ablation of a hypothalamic hamartoma in a patient with a prior temporal lobectomy()

A 19-year-old man with cortical dysplasia and intractable focal seizures underwent a right temporal lobectomy. A hypothalamic hamartoma was subsequently recognized, and he then underwent MRI-guided stereotactic laser ablation. Unfortunately, he sustained damage to the bilateral medial mammillary bod...

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Detalles Bibliográficos
Autores principales: Zubkov, Sarah, Del Bene, Victor A., MacAllister, William S., Shepherd, Timothy M., Devinsky, Orrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536301/
https://www.ncbi.nlm.nih.gov/pubmed/26288758
http://dx.doi.org/10.1016/j.ebcr.2015.07.002
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author Zubkov, Sarah
Del Bene, Victor A.
MacAllister, William S.
Shepherd, Timothy M.
Devinsky, Orrin
author_facet Zubkov, Sarah
Del Bene, Victor A.
MacAllister, William S.
Shepherd, Timothy M.
Devinsky, Orrin
author_sort Zubkov, Sarah
collection PubMed
description A 19-year-old man with cortical dysplasia and intractable focal seizures underwent a right temporal lobectomy. A hypothalamic hamartoma was subsequently recognized, and he then underwent MRI-guided stereotactic laser ablation. Unfortunately, he sustained damage to the bilateral medial mammillary bodies and suffered significant memory loss. We review laser ablation therapy for hypothalamic hamartomas and the anatomy of the memory network. We postulate that his persistent memory disorder resulted from a combination of the right temporal lobectomy and injury to the bilateral medial mammillary bodies.
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spelling pubmed-45363012015-08-18 Disabling amnestic syndrome following stereotactic laser ablation of a hypothalamic hamartoma in a patient with a prior temporal lobectomy() Zubkov, Sarah Del Bene, Victor A. MacAllister, William S. Shepherd, Timothy M. Devinsky, Orrin Epilepsy Behav Case Rep Case Report A 19-year-old man with cortical dysplasia and intractable focal seizures underwent a right temporal lobectomy. A hypothalamic hamartoma was subsequently recognized, and he then underwent MRI-guided stereotactic laser ablation. Unfortunately, he sustained damage to the bilateral medial mammillary bodies and suffered significant memory loss. We review laser ablation therapy for hypothalamic hamartomas and the anatomy of the memory network. We postulate that his persistent memory disorder resulted from a combination of the right temporal lobectomy and injury to the bilateral medial mammillary bodies. Elsevier 2015-08-10 /pmc/articles/PMC4536301/ /pubmed/26288758 http://dx.doi.org/10.1016/j.ebcr.2015.07.002 Text en © 2015 The Authors. Published by Elsevier Inc. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Zubkov, Sarah
Del Bene, Victor A.
MacAllister, William S.
Shepherd, Timothy M.
Devinsky, Orrin
Disabling amnestic syndrome following stereotactic laser ablation of a hypothalamic hamartoma in a patient with a prior temporal lobectomy()
title Disabling amnestic syndrome following stereotactic laser ablation of a hypothalamic hamartoma in a patient with a prior temporal lobectomy()
title_full Disabling amnestic syndrome following stereotactic laser ablation of a hypothalamic hamartoma in a patient with a prior temporal lobectomy()
title_fullStr Disabling amnestic syndrome following stereotactic laser ablation of a hypothalamic hamartoma in a patient with a prior temporal lobectomy()
title_full_unstemmed Disabling amnestic syndrome following stereotactic laser ablation of a hypothalamic hamartoma in a patient with a prior temporal lobectomy()
title_short Disabling amnestic syndrome following stereotactic laser ablation of a hypothalamic hamartoma in a patient with a prior temporal lobectomy()
title_sort disabling amnestic syndrome following stereotactic laser ablation of a hypothalamic hamartoma in a patient with a prior temporal lobectomy()
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536301/
https://www.ncbi.nlm.nih.gov/pubmed/26288758
http://dx.doi.org/10.1016/j.ebcr.2015.07.002
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