Glutamate Acts as a Key Signal Linking Glucose Metabolism to Incretin/cAMP Action to Amplify Insulin Secretion

Incretins, hormones released by the gut after meal ingestion, are essential for maintaining systemic glucose homeostasis by stimulating insulin secretion. The effect of incretins on insulin secretion occurs only at elevated glucose concentrations and is mediated by cAMP signaling, but the mechanism ...

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Detalles Bibliográficos
Autores principales: Gheni, Ghupurjan, Ogura, Masahito, Iwasaki, Masahiro, Yokoi, Norihide, Minami, Kohtaro, Nakayama, Yasumune, Harada, Kazuo, Hastoy, Benoit, Wu, Xichen, Takahashi, Harumi, Kimura, Kazushi, Matsubara, Toshiya, Hoshikawa, Ritsuko, Hatano, Naoya, Sugawara, Kenji, Shibasaki, Tadao, Inagaki, Nobuya, Bamba, Takeshi, Mizoguchi, Akira, Fukusaki, Eiichiro, Rorsman, Patrik, Seino, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536302/
https://www.ncbi.nlm.nih.gov/pubmed/25373904
http://dx.doi.org/10.1016/j.celrep.2014.09.030

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