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Metazoan tRNA introns generate stable circular RNAs in vivo

We report the discovery of a class of abundant circular noncoding RNAs that are produced during metazoan tRNA splicing. These transcripts, termed tRNA intronic circular (tric)RNAs, are conserved features of animal transcriptomes. Biogenesis of tricRNAs requires anciently conserved tRNA sequence moti...

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Detalles Bibliográficos
Autores principales:	Lu, Zhipeng, Filonov, Grigory S., Noto, John J., Schmidt, Casey A., Hatkevich, Talia L., Wen, Ying, Jaffrey, Samie R., Matera, A. Gregory
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2015
Materias:	Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536317/ https://www.ncbi.nlm.nih.gov/pubmed/26194134 http://dx.doi.org/10.1261/rna.052944.115

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