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Differential effects of Ydj1 and Sis1 on Hsp70-mediated clearance of stress granules in Saccharomyces cerevisiae

Stress granules and P-bodies are conserved assemblies of nontranslating mRNAs in eukaryotic cells that can be related to RNA–protein aggregates found in some neurodegenerative diseases. Herein, we examine how the Hsp70/Hsp40 protein chaperones affected the assembly and disassembly of stress granules...

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Detalles Bibliográficos
Autores principales: Walters, Robert W., Muhlrad, Denise, Garcia, Jennifer, Parker, Roy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536325/
https://www.ncbi.nlm.nih.gov/pubmed/26199455
http://dx.doi.org/10.1261/rna.053116.115