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Early Growth Response Genes 2 and 3 Regulate the Expression of Bcl6 and Differentiation of T Follicular Helper Cells
T follicular helper (Tfh) cells support differentiation of B cells to plasma cells and high affinity antibody production in germinal centers (GCs), and Tfh differentiation requires the function of B cell lymphoma 6 (BCL6). We have now discovered that early growth response gene 2 (EGR2) and EGR3 dire...
Autores principales: | Ogbe, Ane, Miao, Tizong, Symonds, Alistair L. J., Omodho, Becky, Singh, Randeep, Bhullar, Punamdip, Li, Suling, Wang, Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536451/ https://www.ncbi.nlm.nih.gov/pubmed/25979336 http://dx.doi.org/10.1074/jbc.M114.634816 |
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