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Blocking Endogenous Leukemia Inhibitory Factor During Placental Development in Mice Leads to Abnormal Placentation and Pregnancy Loss

The placenta forms the interface between the maternal and fetal circulation and is critical for the establishment of a healthy pregnancy. Specialized trophoblast cells derived from the embryonic trophectoderm play a pivotal role in the establishment of the placenta. Leukemia inhibitory factor (LIF)...

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Detalles Bibliográficos
Autores principales: Winship, Amy, Correia, Jeanne, Krishnan, Tara, Menkhorst, Ellen, Cuman, Carly, Zhang, Jian-Guo, Nicola, Nicos A., Dimitriadis, Evdokia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536525/
https://www.ncbi.nlm.nih.gov/pubmed/26272398
http://dx.doi.org/10.1038/srep13237