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Blocking Endogenous Leukemia Inhibitory Factor During Placental Development in Mice Leads to Abnormal Placentation and Pregnancy Loss
The placenta forms the interface between the maternal and fetal circulation and is critical for the establishment of a healthy pregnancy. Specialized trophoblast cells derived from the embryonic trophectoderm play a pivotal role in the establishment of the placenta. Leukemia inhibitory factor (LIF)...
Autores principales: | Winship, Amy, Correia, Jeanne, Krishnan, Tara, Menkhorst, Ellen, Cuman, Carly, Zhang, Jian-Guo, Nicola, Nicos A., Dimitriadis, Evdokia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536525/ https://www.ncbi.nlm.nih.gov/pubmed/26272398 http://dx.doi.org/10.1038/srep13237 |
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