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Intestinal macrophages arising from CCR2(+) monocytes control pathogen infection by activating innate lymphoid cells

Monocytes play a crucial role in antimicrobial host defence, but the mechanisms by which they protect the host during intestinal infection remains poorly understood. Here we show that depletion of CCR2(+) monocytes results in impaired clearance of the intestinal pathogen Citrobacter rodentium. After...

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Detalles Bibliográficos
Autores principales: Seo, Sang-Uk, Kuffa, Peter, Kitamoto, Sho, Nagao-Kitamoto, Hiroko, Rousseau, Jenna, Kim, Yun-Gi, Núñez, Gabriel, Kamada, Nobuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536571/
https://www.ncbi.nlm.nih.gov/pubmed/26269452
http://dx.doi.org/10.1038/ncomms9010

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