Cargando…
Intestinal macrophages arising from CCR2(+) monocytes control pathogen infection by activating innate lymphoid cells
Monocytes play a crucial role in antimicrobial host defence, but the mechanisms by which they protect the host during intestinal infection remains poorly understood. Here we show that depletion of CCR2(+) monocytes results in impaired clearance of the intestinal pathogen Citrobacter rodentium. After...
Autores principales: | Seo, Sang-Uk, Kuffa, Peter, Kitamoto, Sho, Nagao-Kitamoto, Hiroko, Rousseau, Jenna, Kim, Yun-Gi, Núñez, Gabriel, Kamada, Nobuhiko |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536571/ https://www.ncbi.nlm.nih.gov/pubmed/26269452 http://dx.doi.org/10.1038/ncomms9010 |
Ejemplares similares
-
Pathogenic role of the gut microbiota in gastrointestinal diseases
por: Nagao-Kitamoto, Hiroko, et al.
Publicado: (2016) -
Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine
por: Ochi, Takanori, et al.
Publicado: (2016) -
IL-10 produced by macrophages regulates epithelial integrity in the small intestine
por: Morhardt, Tina L., et al.
Publicado: (2019) -
Flagellin-mediated activation of IL-33-ST2 signaling by a pathobiont promotes intestinal fibrosis
por: Imai, Jin, et al.
Publicado: (2019) -
Host-microbial Cross-talk in Inflammatory Bowel Disease
por: Nagao-Kitamoto, Hiroko, et al.
Publicado: (2017)