Complete Genome Sequences of Low-Passage Virulent and High-Passage Avirulent Variants of Pathogenic Leptospira interrogans Serovar Manilae Strain UP-MMC-NIID, Originally Isolated from a Patient with Severe Leptospirosis, Determined Using PacBio Single-Molecule Real-Time Technology

Here, we report the complete genome sequences of low-passage virulent and high-passage avirulent variants of pathogenic Leptospira interrogans serovar Manilae strain UP-MMC-NIID, a major causative agent of leptospirosis. While there were no major differences between the genome sequences, the levels...

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Autores principales: Satou, Kazuhito, Shimoji, Makiko, Tamotsu, Hinako, Juan, Ayaka, Ashimine, Noriko, Shinzato, Misuzu, Toma, Claudia, Nohara, Toshitsugu, Shiroma, Akino, Nakano, Kazuma, Teruya, Kuniko, Terabayashi, Yasunobu, Ohki, Shun, Koizumi, Nobuo, Okano, Shou, Suzuki, Toshihiko, Hirano, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Prokaryotes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536678/
https://www.ncbi.nlm.nih.gov/pubmed/26272567
http://dx.doi.org/10.1128/genomeA.00882-15
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author Satou, Kazuhito
Shimoji, Makiko
Tamotsu, Hinako
Juan, Ayaka
Ashimine, Noriko
Shinzato, Misuzu
Toma, Claudia
Nohara, Toshitsugu
Shiroma, Akino
Nakano, Kazuma
Teruya, Kuniko
Terabayashi, Yasunobu
Ohki, Shun
Koizumi, Nobuo
Okano, Shou
Suzuki, Toshihiko
Hirano, Takashi
author_facet Satou, Kazuhito
Shimoji, Makiko
Tamotsu, Hinako
Juan, Ayaka
Ashimine, Noriko
Shinzato, Misuzu
Toma, Claudia
Nohara, Toshitsugu
Shiroma, Akino
Nakano, Kazuma
Teruya, Kuniko
Terabayashi, Yasunobu
Ohki, Shun
Koizumi, Nobuo
Okano, Shou
Suzuki, Toshihiko
Hirano, Takashi
author_sort Satou, Kazuhito
collection PubMed
description Here, we report the complete genome sequences of low-passage virulent and high-passage avirulent variants of pathogenic Leptospira interrogans serovar Manilae strain UP-MMC-NIID, a major causative agent of leptospirosis. While there were no major differences between the genome sequences, the levels of base modifications were higher in the avirulent variant.
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spelling pubmed-45366782015-08-19 Complete Genome Sequences of Low-Passage Virulent and High-Passage Avirulent Variants of Pathogenic Leptospira interrogans Serovar Manilae Strain UP-MMC-NIID, Originally Isolated from a Patient with Severe Leptospirosis, Determined Using PacBio Single-Molecule Real-Time Technology Satou, Kazuhito Shimoji, Makiko Tamotsu, Hinako Juan, Ayaka Ashimine, Noriko Shinzato, Misuzu Toma, Claudia Nohara, Toshitsugu Shiroma, Akino Nakano, Kazuma Teruya, Kuniko Terabayashi, Yasunobu Ohki, Shun Koizumi, Nobuo Okano, Shou Suzuki, Toshihiko Hirano, Takashi Genome Announc Prokaryotes Here, we report the complete genome sequences of low-passage virulent and high-passage avirulent variants of pathogenic Leptospira interrogans serovar Manilae strain UP-MMC-NIID, a major causative agent of leptospirosis. While there were no major differences between the genome sequences, the levels of base modifications were higher in the avirulent variant. American Society for Microbiology 2015-08-13 /pmc/articles/PMC4536678/ /pubmed/26272567 http://dx.doi.org/10.1128/genomeA.00882-15 Text en Copyright © 2015 Satou et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license (http://creativecommons.org/licenses/by/3.0/) .
spellingShingle Prokaryotes
Satou, Kazuhito
Shimoji, Makiko
Tamotsu, Hinako
Juan, Ayaka
Ashimine, Noriko
Shinzato, Misuzu
Toma, Claudia
Nohara, Toshitsugu
Shiroma, Akino
Nakano, Kazuma
Teruya, Kuniko
Terabayashi, Yasunobu
Ohki, Shun
Koizumi, Nobuo
Okano, Shou
Suzuki, Toshihiko
Hirano, Takashi
Complete Genome Sequences of Low-Passage Virulent and High-Passage Avirulent Variants of Pathogenic Leptospira interrogans Serovar Manilae Strain UP-MMC-NIID, Originally Isolated from a Patient with Severe Leptospirosis, Determined Using PacBio Single-Molecule Real-Time Technology
title Complete Genome Sequences of Low-Passage Virulent and High-Passage Avirulent Variants of Pathogenic Leptospira interrogans Serovar Manilae Strain UP-MMC-NIID, Originally Isolated from a Patient with Severe Leptospirosis, Determined Using PacBio Single-Molecule Real-Time Technology
title_full Complete Genome Sequences of Low-Passage Virulent and High-Passage Avirulent Variants of Pathogenic Leptospira interrogans Serovar Manilae Strain UP-MMC-NIID, Originally Isolated from a Patient with Severe Leptospirosis, Determined Using PacBio Single-Molecule Real-Time Technology
title_fullStr Complete Genome Sequences of Low-Passage Virulent and High-Passage Avirulent Variants of Pathogenic Leptospira interrogans Serovar Manilae Strain UP-MMC-NIID, Originally Isolated from a Patient with Severe Leptospirosis, Determined Using PacBio Single-Molecule Real-Time Technology
title_full_unstemmed Complete Genome Sequences of Low-Passage Virulent and High-Passage Avirulent Variants of Pathogenic Leptospira interrogans Serovar Manilae Strain UP-MMC-NIID, Originally Isolated from a Patient with Severe Leptospirosis, Determined Using PacBio Single-Molecule Real-Time Technology
title_short Complete Genome Sequences of Low-Passage Virulent and High-Passage Avirulent Variants of Pathogenic Leptospira interrogans Serovar Manilae Strain UP-MMC-NIID, Originally Isolated from a Patient with Severe Leptospirosis, Determined Using PacBio Single-Molecule Real-Time Technology
title_sort complete genome sequences of low-passage virulent and high-passage avirulent variants of pathogenic leptospira interrogans serovar manilae strain up-mmc-niid, originally isolated from a patient with severe leptospirosis, determined using pacbio single-molecule real-time technology
topic Prokaryotes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536678/
https://www.ncbi.nlm.nih.gov/pubmed/26272567
http://dx.doi.org/10.1128/genomeA.00882-15
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