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Key fibrogenic mediators: old players. Renin–angiotensin system

Interstitial fibrosis represents the final common pathway of any form of progressive renal disease. The severity of tubular interstitial damage is highly correlated to the degree of decline of renal function, even better than the glomerular lesions do. Angiotensin II (Ang II), the main effector of t...

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Detalles Bibliográficos
Autores principales: Macconi, Daniela, Remuzzi, Giuseppe, Benigni, Ariela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536968/
https://www.ncbi.nlm.nih.gov/pubmed/26312151
http://dx.doi.org/10.1038/kisup.2014.11