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Key fibrogenic mediators: old players. Renin–angiotensin system
Interstitial fibrosis represents the final common pathway of any form of progressive renal disease. The severity of tubular interstitial damage is highly correlated to the degree of decline of renal function, even better than the glomerular lesions do. Angiotensin II (Ang II), the main effector of t...
Autores principales: | Macconi, Daniela, Remuzzi, Giuseppe, Benigni, Ariela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536968/ https://www.ncbi.nlm.nih.gov/pubmed/26312151 http://dx.doi.org/10.1038/kisup.2014.11 |
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