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New dimension in therapeutic targeting of BCL-2 family proteins
Proteins of the BCL-2 family control the mitochondrial pathway of apoptosis. Targeting these proteins proves to be an attractive strategy for anticancer therapy. The biological context is based on the fact that BH3-only members of the family are specific antagonists of prosurvival members. This prom...
Autores principales: | Besbes, Samaher, Mirshahi, Massoud, Pocard, Marc, Billard, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536985/ https://www.ncbi.nlm.nih.gov/pubmed/25970783 |
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