Cargando…
Deubiquitinases in cancer
Deubiquitinases are deubiquitinating enzymes (DUBs), which remove ubiquitin from proteins, thus regulating their proteasomal degradation, localization and activity. Here, we discuss DUBs as anti-cancer drug targets.
| Autores principales: | , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536986/ https://www.ncbi.nlm.nih.gov/pubmed/25972356 |
| _version_ | 1782385825652146176 |
|---|---|
| author | Wei, Rongbin Liu, Xiaodong Yu, Weixin Yang, Tianshu Cai, Wenping Liu, Junjun Huang, Xiao Xu, Guo-tong Zhao, Shouliang Yang, Jianhua Liu, Shangfeng |
| author_facet | Wei, Rongbin Liu, Xiaodong Yu, Weixin Yang, Tianshu Cai, Wenping Liu, Junjun Huang, Xiao Xu, Guo-tong Zhao, Shouliang Yang, Jianhua Liu, Shangfeng |
| author_sort | Wei, Rongbin |
| collection | PubMed |
| description | Deubiquitinases are deubiquitinating enzymes (DUBs), which remove ubiquitin from proteins, thus regulating their proteasomal degradation, localization and activity. Here, we discuss DUBs as anti-cancer drug targets. |
| format | Online Article Text |
| id | pubmed-4536986 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2015 |
| publisher | Impact Journals LLC |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-45369862015-08-26 Deubiquitinases in cancer Wei, Rongbin Liu, Xiaodong Yu, Weixin Yang, Tianshu Cai, Wenping Liu, Junjun Huang, Xiao Xu, Guo-tong Zhao, Shouliang Yang, Jianhua Liu, Shangfeng Oncotarget Review Deubiquitinases are deubiquitinating enzymes (DUBs), which remove ubiquitin from proteins, thus regulating their proteasomal degradation, localization and activity. Here, we discuss DUBs as anti-cancer drug targets. Impact Journals LLC 2015-05-07 /pmc/articles/PMC4536986/ /pubmed/25972356 Text en Copyright: © 2015 Wei et al. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
| spellingShingle | Review Wei, Rongbin Liu, Xiaodong Yu, Weixin Yang, Tianshu Cai, Wenping Liu, Junjun Huang, Xiao Xu, Guo-tong Zhao, Shouliang Yang, Jianhua Liu, Shangfeng Deubiquitinases in cancer |
| title | Deubiquitinases in cancer |
| title_full | Deubiquitinases in cancer |
| title_fullStr | Deubiquitinases in cancer |
| title_full_unstemmed | Deubiquitinases in cancer |
| title_short | Deubiquitinases in cancer |
| title_sort | deubiquitinases in cancer |
| topic | Review |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536986/ https://www.ncbi.nlm.nih.gov/pubmed/25972356 |
| work_keys_str_mv | AT weirongbin deubiquitinasesincancer AT liuxiaodong deubiquitinasesincancer AT yuweixin deubiquitinasesincancer AT yangtianshu deubiquitinasesincancer AT caiwenping deubiquitinasesincancer AT liujunjun deubiquitinasesincancer AT huangxiao deubiquitinasesincancer AT xuguotong deubiquitinasesincancer AT zhaoshouliang deubiquitinasesincancer AT yangjianhua deubiquitinasesincancer AT liushangfeng deubiquitinasesincancer |