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Bruton's tyrosine kinase (Btk) inhibitor ibrutinib suppresses stem-like traits in ovarian cancer

According to a Prognoscan database, upregulation of Bruton's tyrosine kinase (Btk) is associated with low overall survival in ovarian cancer patients. We found that spheroids-forming ovarian cancer cell, which highly expressed cancer stem-like cell (CSC) markers and Btk, were cisplatin resistan...

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Detalles Bibliográficos
Autores principales:	Zucha, Muhammad Ary, Wu, Alexander T.H., Lee, Wei-Hwa, Wang, Liang-Shun, Lin, Wan-Wan, Yuan, Chiou-Chung, Yeh, Chi-Tai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537012/ https://www.ncbi.nlm.nih.gov/pubmed/26036311

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