Tyrosine dephosphorylation enhances the therapeutic target activity of epidermal growth factor receptor (EGFR) by disrupting its interaction with estrogen receptor (ER)

Protein-protein interactions can increase or decrease its therapeutic target activity and the determining factors involved, however, are largely unknown. Here, we report that tyrosine-dephosphorylation of epidermal growth factor receptor (EGFR) increases its therapeutic target activity by disrupting...

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Detalles Bibliográficos
Autores principales: Ma, Shao, Yin, Ning, Qi, Xiaomei, Pfister, Sandra L., Zhang, Mei-Jie, Ma, Rong, Chen, Guan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537017/
https://www.ncbi.nlm.nih.gov/pubmed/26079946

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