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Effects of RAL signal transduction in KRAS- and BRAF-mutated cells and prognostic potential of the RAL signature in colorectal cancer

Our understanding of oncogenic signaling pathways has strongly fostered current concepts for targeted therapies in metastatic colorectal cancer. The RALA pathway is novel candidate due to its independent role in controlling expression of genes downstream of RAS. We compared RALA GTPase activities in...

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Detalles Bibliográficos
Autores principales:	Győrffy, Balázs, Stelniec-Klotz, Iwona, Sigler, Christian, Kasack, Katharina, Redmer, Torben, Qian, Yu, Schäfer, Reinhold
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537018/ https://www.ncbi.nlm.nih.gov/pubmed/26033452

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