Deregulation of PPARβ/δ target genes in tumor-associated macrophages by fatty acid ligands in the ovarian cancer microenvironment

The nuclear receptor peroxisome proliferator-activated receptor β/δ (PPARβ/δ) is a lipid ligand-inducible transcription factor associated with macrophage polarization. However, its function in tumor-associated macrophages (TAMs) has not been investigated to date. Here, we report the PPARβ/δ-regulate...

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Detalles Bibliográficos
Autores principales: Schumann, Tim, Adhikary, Till, Wortmann, Annika, Finkernagel, Florian, Lieber, Sonja, Schnitzer, Evelyn, Legrand, Nathalie, Schober, Yvonne, Nockher, W. Andreas, Toth, Philipp M., Diederich, Wibke E., Nist, Andrea, Stiewe, Thorsten, Wagner, Uwe, Reinartz, Silke, Müller-Brüsselbach, Sabine, Müller, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537024/
https://www.ncbi.nlm.nih.gov/pubmed/25968567

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