By reducing hexokinase 2, resveratrol induces apoptosis in HCC cells addicted to aerobic glycolysis and inhibits tumor growth in mice

Cancer cells exhibit an altered metabolic phenotype known as the aerobic glycolysis. The expression of HK2 changes the metabolic phenotype of cells to support cancerous growth. In the present study, we investigated the inhibitory effect of resveratrol on HK2 expression and hepatocellular carcinoma (...

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Detalles Bibliográficos
Autores principales: Dai, Weiqi, Wang, Fan, Lu, Jie, Xia, Yujing, He, Lei, Chen, Kan, Li, Jingjing, Li, Sainan, Liu, Tong, Zheng, Yuanyuan, Wang, Jianrong, Lu, Wenxia, Zhou, Yuqing, Yin, Qin, Abudumijiti, Huerxidan, Chen, Rongxia, Zhang, Rong, Zhou, Li, Zhou, Zheng, Zhu, Rong, Yang, Jing, Wang, Chengfen, Zhang, Huawei, Zhou, Yingqun, Xu, Ling, Guo, Chuanyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537043/
https://www.ncbi.nlm.nih.gov/pubmed/25938543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537043/
https://www.ncbi.nlm.nih.gov/pubmed/25938543

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