Involvement of multiple myeloma cell-derived exosomes in osteoclast differentiation

Bone disease is the most frequent complication in multiple myeloma (MM) resulting in osteolytic lesions, bone pain, hypercalcemia and renal failure. In MM bone disease the perfect balance between bone-resorbing osteoclasts (OCs) and bone-forming osteoblasts (OBs) activity is lost in favour of OCs, t...

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Detalles Bibliográficos
Autores principales: Raimondi, Lavinia, De Luca, Angela, Amodio, Nicola, Manno, Mauro, Raccosta, Samuele, Taverna, Simona, Bellavia, Daniele, Naselli, Flores, Fontana, Simona, Schillaci, Odessa, Giardino, Roberto, Fini, Milena, Tassone, Pierfrancesco, Santoro, Alessandra, De Leo, Giacomo, Giavaresi, Gianluca, Alessandro, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537049/
https://www.ncbi.nlm.nih.gov/pubmed/25944696

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