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Heme Signaling Impacts Global Gene Expression, Immunity and Dengue Virus Infectivity in Aedes aegypti
Blood-feeding mosquitoes are exposed to high levels of heme, the product of hemoglobin degradation. Heme is a pro-oxidant that influences a variety of cellular processes. We performed a global analysis of heme-regulated Aedes aegypti (yellow fever mosquito) transcriptional changes to better understa...
Autores principales: | Bottino-Rojas, Vanessa, Talyuli, Octávio A. C., Jupatanakul, Natapong, Sim, Shuzhen, Dimopoulos, George, Venancio, Thiago M., Bahia, Ana C., Sorgine, Marcos H., Oliveira, Pedro L., Paiva-Silva, Gabriela O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537099/ https://www.ncbi.nlm.nih.gov/pubmed/26275150 http://dx.doi.org/10.1371/journal.pone.0135985 |
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