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Progressive Hemorrhage and Myotoxicity Induced by Echis carinatus Venom in Murine Model: Neutralization by Inhibitor Cocktail of N,N,N',N'-Tetrakis (2-Pyridylmethyl) Ethane-1,2-Diamine and Silymarin
Viperbite is often associated with severe local toxicity, including progressive hemorrhage and myotoxicity, persistent even after the administration of anti-snake venom (ASV). In the recent past, investigations have revealed the orchestrated actions of Zn(2+) metalloproteases (Zn(2+)MPs), phospholip...
Autores principales: | Nanjaraj Urs, Ankanahalli N., Ramakrishnan, Chandrasekaran, Joshi, Vikram, Suvilesh, Kanve Nagaraj, Veerabasappa Gowda, Teregowda, Velmurugan, Devadasan, Vishwanath, Bannikuppe Sannanaik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537139/ https://www.ncbi.nlm.nih.gov/pubmed/26274501 http://dx.doi.org/10.1371/journal.pone.0135843 |
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