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Curation of the Mammalian Palmitoylome Indicates a Pivotal Role for Palmitoylation in Diseases and Disorders of the Nervous System and Cancers

Palmitoylation involves the reversible posttranslational addition of palmitate to cysteines and promotes membrane binding and subcellular localization. Recent advancements in the detection and identification of palmitoylated proteins have led to multiple palmitoylation proteomics studies but these d...

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Detalles Bibliográficos
Autores principales: Sanders, Shaun S., Martin, Dale D. O., Butland, Stefanie L., Lavallée-Adam, Mathieu, Calzolari, Diego, Kay, Chris, Yates, John R., Hayden, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537140/
https://www.ncbi.nlm.nih.gov/pubmed/26275289
http://dx.doi.org/10.1371/journal.pcbi.1004405