Real-Time PCR Quantification of Heteroplasmy in a Mouse Model with Mitochondrial DNA of C57BL/6 and NZB/BINJ Strains

Mouse models are widely employed to study mitochondrial inheritance, which have implications to several human diseases caused by mutations in the mitochondrial genome (mtDNA). These mouse models take advantage of polymorphisms between the mtDNA of the NZB/BINJ and the mtDNA of common inbred laborato...

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Detalles Bibliográficos
Autores principales: Machado, Thiago Simões, Macabelli, Carolina Habermann, Sangalli, Juliano Rodrigues, Rodrigues, Thiago Bittencourt, Smith, Lawrence Charles, Meirelles, Flávio Vieira, Chiaratti, Marcos Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537288/
https://www.ncbi.nlm.nih.gov/pubmed/26274500
http://dx.doi.org/10.1371/journal.pone.0133650

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