Cargando…

Dichloroacetate Decreases Cell Health and Activates Oxidative Stress Defense Pathways in Rat Alveolar Type II Pneumocytes

Dichloroacetate (DCA) is a water purification byproduct that is known to be hepatotoxic and hepatocarcinogenic and to induce peripheral neuropathy and damage macrophages. This study characterizes the effects of the haloacetate on lung cells by exposing rat alveolar type II (L2) cells to 0–24 mM DCA...

Descripción completa

Detalles Bibliográficos
Autores principales: Valauri-Orton, Alexis, Bschorer, Frizzi, Bernd, Karen K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537706/
https://www.ncbi.nlm.nih.gov/pubmed/26301238
http://dx.doi.org/10.1155/2015/129031