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Brain-Specific Superoxide Dismutase 2 Deficiency Causes Perinatal Death with Spongiform Encephalopathy in Mice
Oxidative stress is believed to greatly contribute to the pathogenesis of various diseases, including neurodegeneration. Impairment of mitochondrial energy production and increased mitochondrial oxidative damage are considered early pathological events that lead to neurodegeneration. Manganese super...
Autores principales: | Izuo, Naotaka, Nojiri, Hidetoshi, Uchiyama, Satoshi, Noda, Yoshihiro, Kawakami, Satoru, Kojima, Shuji, Sasaki, Toru, Shirasawa, Takuji, Shimizu, Takahiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537744/ https://www.ncbi.nlm.nih.gov/pubmed/26301039 http://dx.doi.org/10.1155/2015/238914 |
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