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Clinical Experience of Patients Referred to a Multidisciplinary Cardiac Oncology Clinic: An Observational Study

Cardiotoxicity is the second leading cause of long-term morbidity and mortality among cancer survivors. The purpose of this retrospective observational study is to report on the clinical and cardiac outcomes in patients with early stage and advanced cancer who were referred to our multidisciplinary...

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Autores principales: Sulpher, Jeffrey, Mathur, Shrey, Graham, Nadine, Crawley, Freya, Turek, Michele, Johnson, Christopher, Stadnick, Ellamae, Law, Angeline, Wentzell, Jason, Dent, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537752/
https://www.ncbi.nlm.nih.gov/pubmed/26300917
http://dx.doi.org/10.1155/2015/671232
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author Sulpher, Jeffrey
Mathur, Shrey
Graham, Nadine
Crawley, Freya
Turek, Michele
Johnson, Christopher
Stadnick, Ellamae
Law, Angeline
Wentzell, Jason
Dent, Susan
author_facet Sulpher, Jeffrey
Mathur, Shrey
Graham, Nadine
Crawley, Freya
Turek, Michele
Johnson, Christopher
Stadnick, Ellamae
Law, Angeline
Wentzell, Jason
Dent, Susan
author_sort Sulpher, Jeffrey
collection PubMed
description Cardiotoxicity is the second leading cause of long-term morbidity and mortality among cancer survivors. The purpose of this retrospective observational study is to report on the clinical and cardiac outcomes in patients with early stage and advanced cancer who were referred to our multidisciplinary cardiac oncology clinic (COC). A total of 428 patients were referred to the COC between October 2008 and January 2013. The median age of patients at time of cancer diagnosis was 60. Almost half of patients who received cancer therapy received first-line chemotherapy alone (169, 41.7%), of which 84 (49.7%) were exposed to anthracyclines. The most common reasons for referral to the cardiac oncology clinic were decreased LVEF (34.6%), prechemotherapy assessment (11.9%), and arrhythmia (8.4%). A total of 175 (40.9%) patients referred to the COC were treated with cardiac medications. The majority (331, 77.3%) of patients were alive as of January 2013, and 93 (21.7%) patients were deceased. Through regular review of cardiac oncology clinic referral patterns, management plans, and patient outcomes, we aim to continuously improve delivery of cardiac care to our patient population and optimize cardiac health.
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spelling pubmed-45377522015-08-23 Clinical Experience of Patients Referred to a Multidisciplinary Cardiac Oncology Clinic: An Observational Study Sulpher, Jeffrey Mathur, Shrey Graham, Nadine Crawley, Freya Turek, Michele Johnson, Christopher Stadnick, Ellamae Law, Angeline Wentzell, Jason Dent, Susan J Oncol Research Article Cardiotoxicity is the second leading cause of long-term morbidity and mortality among cancer survivors. The purpose of this retrospective observational study is to report on the clinical and cardiac outcomes in patients with early stage and advanced cancer who were referred to our multidisciplinary cardiac oncology clinic (COC). A total of 428 patients were referred to the COC between October 2008 and January 2013. The median age of patients at time of cancer diagnosis was 60. Almost half of patients who received cancer therapy received first-line chemotherapy alone (169, 41.7%), of which 84 (49.7%) were exposed to anthracyclines. The most common reasons for referral to the cardiac oncology clinic were decreased LVEF (34.6%), prechemotherapy assessment (11.9%), and arrhythmia (8.4%). A total of 175 (40.9%) patients referred to the COC were treated with cardiac medications. The majority (331, 77.3%) of patients were alive as of January 2013, and 93 (21.7%) patients were deceased. Through regular review of cardiac oncology clinic referral patterns, management plans, and patient outcomes, we aim to continuously improve delivery of cardiac care to our patient population and optimize cardiac health. Hindawi Publishing Corporation 2015 2015-08-02 /pmc/articles/PMC4537752/ /pubmed/26300917 http://dx.doi.org/10.1155/2015/671232 Text en Copyright © 2015 Jeffrey Sulpher et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Sulpher, Jeffrey
Mathur, Shrey
Graham, Nadine
Crawley, Freya
Turek, Michele
Johnson, Christopher
Stadnick, Ellamae
Law, Angeline
Wentzell, Jason
Dent, Susan
Clinical Experience of Patients Referred to a Multidisciplinary Cardiac Oncology Clinic: An Observational Study
title Clinical Experience of Patients Referred to a Multidisciplinary Cardiac Oncology Clinic: An Observational Study
title_full Clinical Experience of Patients Referred to a Multidisciplinary Cardiac Oncology Clinic: An Observational Study
title_fullStr Clinical Experience of Patients Referred to a Multidisciplinary Cardiac Oncology Clinic: An Observational Study
title_full_unstemmed Clinical Experience of Patients Referred to a Multidisciplinary Cardiac Oncology Clinic: An Observational Study
title_short Clinical Experience of Patients Referred to a Multidisciplinary Cardiac Oncology Clinic: An Observational Study
title_sort clinical experience of patients referred to a multidisciplinary cardiac oncology clinic: an observational study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537752/
https://www.ncbi.nlm.nih.gov/pubmed/26300917
http://dx.doi.org/10.1155/2015/671232
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