Cargando…

Complex Inflammation mRNA-Related Response in ALS Is Region Dependent

Inflammatory changes are analyzed in the anterior spinal cord and frontal cortex area 8 in typical spinal-predominant ALS cases. Increased numbers of astrocytes and activated microglia are found in the anterior horn of the spinal cord and pyramidal tracts. Significant increased expression of TLR7, C...

Descripción completa

Detalles Bibliográficos
Autores principales:	Berjaoui, Sara, Povedano, Mónica, Garcia-Esparcia, Paula, Carmona, Margarita, Aso, Ester, Ferrer, Isidre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537753/ https://www.ncbi.nlm.nih.gov/pubmed/26301107 http://dx.doi.org/10.1155/2015/573784

Ejemplares similares

Altered machinery of protein synthesis is region- and stage-dependent and is associated with α-synuclein oligomers in Parkinson’s disease
por: Garcia-Esparcia, Paula, et al.
Publicado: (2015)

Genetic and Transcriptomic Profiles of Inflammation in Neurodegenerative Diseases: Alzheimer, Parkinson, Creutzfeldt-Jakob and Tauopathies
por: López González, Irene, et al.
Publicado: (2016)

TDP-43 Vasculopathy in the Spinal Cord in Sporadic Amyotrophic Lateral Sclerosis (sALS) and Frontal Cortex in sALS/FTLD-TDP
por: Ferrer, Isidro, et al.
Publicado: (2021)

Cannabinoids for treatment of Alzheimer’s disease: moving toward the clinic
por: Aso, Ester, et al.
Publicado: (2014)

Amyotrophic lateral sclerosis, gene deregulation in the anterior horn of the spinal cord and frontal cortex area 8: implications in frontotemporal lobar degeneration
por: Andrés-Benito, Pol, et al.
Publicado: (2017)

In situ structural characterization of early amyloid aggregates in Alzheimer’s disease transgenic mice and Octodon degus
por: Benseny-Cases, Núria, et al.
Publicado: (2020)

Retraction Note: In situ structural characterization of early amyloid aggregates in Alzheimer’s disease transgenic mice and Octodon degus
por: Benseny-Cases, Núria, et al.
Publicado: (2020)

In situ identification and G4-PPI-His-Mal-dendrimer-induced reduction of early-stage amyloid aggregates in Alzheimer’s disease transgenic mice using synchrotron-based infrared imaging
por: Benseny-Cases, Núria, et al.
Publicado: (2021)

Inflammatory Gene Expression in Whole Peripheral Blood at Early Stages of Sporadic Amyotrophic Lateral Sclerosis
por: Andrés-Benito, Pol, et al.
Publicado: (2017)

Hemoglobin mRNA Changes in the Frontal Cortex of Patients with Neurodegenerative Diseases
por: Vanni, Silvia, et al.
Publicado: (2018)

Promoter Hypermethylation of the Phosphatase DUSP22 Mediates PKA-Dependent TAU Phosphorylation and CREB Activation in Alzheimer's Disease
por: Sanchez-Mut, Jose Vicente, et al.
Publicado: (2014)

Subtype and Regional-Specific Neuroinflammation in Sporadic Creutzfeldt–Jakob Disease
por: Llorens, Franc, et al.
Publicado: (2014)

YKL40 in sporadic amyotrophic lateral sclerosis: cerebrospinal fluid levels as a prognosis marker of disease progression
por: Andrés-Benito, Pol, et al.
Publicado: (2018)

Correction for: YKL40 in sporadic amyotrophic lateral sclerosis: cerebrospinal fluid levels as a prognosis marker of disease progression
por: Andrés‐Benito, Pol, et al.
Publicado: (2021)

Early and gender-specific differences in spinal cord mitochondrial function and oxidative stress markers in a mouse model of ALS
por: Cacabelos, Daniel, et al.
Publicado: (2016)

Glutamate Transporter GLT1 Expression in Alzheimer Disease and Dementia With Lewy Bodies
por: Garcia-Esparcia, Paula, et al.
Publicado: (2018)

Olfactory Receptors in Non-Chemosensory Organs: The Nervous System in Health and Disease
por: Ferrer, Isidro, et al.
Publicado: (2016)

Evaluation of Chemokine mRNA Expression to Assess Allergic Inflammation of the Ocular Surface in Chronic Allergic Conjunctival Diseases
por: Aso, Hiroshi, et al.
Publicado: (2019)

Involvement of Oligodendrocytes in Tau Seeding and Spreading in Tauopathies
por: Ferrer, Isidro, et al.
Publicado: (2019)

Disease-Specific Changes in Reelin Protein and mRNA in Neurodegenerative Diseases
por: Lidón, Laia, et al.
Publicado: (2020)

Differences in Tau Seeding in Newborn and Adult Wild-Type Mice
por: Ferrer, Isidro, et al.
Publicado: (2022)

CB(2) Cannabinoid Receptor As Potential Target against Alzheimer's Disease
por: Aso, Ester, et al.
Publicado: (2016)

Control of mRNA Translation in ALS Proteinopathy
por: Cestra, Gianluca, et al.
Publicado: (2017)

Optimization of mRNA untranslated regions for improved expression of therapeutic mRNA
por: Asrani, Kirtika H., et al.
Publicado: (2018)

Proteostatic modulation in brain aging without associated Alzheimer’s disease-and age-related neuropathological changes
por: Andrés-Benito, Pol, et al.
Publicado: (2023)

The role of mRNA degradation in immunity and inflammation
por: Akira, Shizuo
Publicado: (2012)

Cardiovascular disease, inflammation, and mRNA stability
por: Herman, Allison B., et al.
Publicado: (2018)

Azithromycin decreases NALP3 mRNA stability in monocytes to limit inflammasome-dependent inflammation
por: Lendermon, Elizabeth A., et al.
Publicado: (2017)

mRNA-Based Nanomedicinal Products to Address Corneal Inflammation by Interleukin-10 Supplementation
por: Gómez-Aguado, Itziar, et al.
Publicado: (2021)

A motor neuron disease mouse model reveals a non-canonical profile of senescence biomarkers
por: Torres, Pascual, et al.
Publicado: (2022)

A manganese-dependent ribozyme in the 3′-untranslated region of Xenopus Vg1 mRNA
por: Kolev, Nikolay G., et al.
Publicado: (2008)

Structural Characteristics of the 5′-Terminal Region of Mouse p53 mRNA and Identification of Proteins That Bind to This mRNA Region
por: Szpotkowska, Joanna, et al.
Publicado: (2022)

TDP-43 Cytoplasmic Translocation in the Skin Fibroblasts of ALS Patients
por: Rubio, Miguel A., et al.
Publicado: (2022)

Recruitment of two dyneins to an mRNA-dependent Bicaudal D transport complex
por: Sladewski, Thomas E, et al.
Publicado: (2018)

ZMPSTE24 Is Associated with Elevated Inflammation and Progerin mRNA
por: Messner, Moritz, et al.
Publicado: (2020)

Lipid alterations in human frontal cortex in ALS‐FTLD‐TDP43 proteinopathy spectrum are partly related to peroxisome impairment
por: Andrés‐Benito, Pol, et al.
Publicado: (2021)

Dementia with Lewy Bodies: Molecular Pathology in the Frontal Cortex in Typical and Rapidly Progressive Forms
por: Garcia-Esparcia, Paula, et al.
Publicado: (2017)

Complex regional pain syndrome after mRNA-based COVID-19 vaccination
por: Horisawa, Shiro, et al.
Publicado: (2023)

Actin and Myosin-Dependent Localization of mRNA to Dendrites
por: Balasanyan, Varuzhan, et al.
Publicado: (2014)

Quantitating translational control: mRNA abundance-dependent and independent contributions and the mRNA sequences that specify them
por: Li, Jingyi Jessica, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_p99ts5n9tl8sq0samrm3bdqgem