ERK-regulated αB-Crystallin Induction by Matrix Detachment Inhibits Anoikis and Promotes Lung Metastasis in vivo

Evasion of extracellular matrix detachment-induced apoptosis (“anoikis”) is a defining characteristic of metastatic tumor cells. The ability of metastatic carcinoma cells to survive matrix detachment and escape anoikis enables them to disseminate as viable circulating tumor cells and seed distant or...

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Detalles Bibliográficos
Autores principales: Malin, Dmitry, Strekalova, Elena, Petrovic, Vladimir, Rajanala, Harisha, Sharma, Bhawna, Ugolkov, Andrey, Gradishar, William J., Cryns, Vincent L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537846/
https://www.ncbi.nlm.nih.gov/pubmed/25684139
http://dx.doi.org/10.1038/onc.2015.12

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