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Systemic exposure to menthol following administration of peppermint oil to paediatric patients

OBJECTIVE: Peppermint oil (PMO) has been used to treat abdominal ailments dating to ancient Egypt, Greece and Rome. Despite its increasing paediatric use, as in irritable bowel syndrome (IBS) treatment, the pharmacokinetics (PK) of menthol in children given PMO has not been explored. DESIGN AND SETT...

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Detalles Bibliográficos
Autores principales:	Kearns, Gregory L, Chumpitazi, Bruno Pedro, Abdel-Rahman, Susan M, Garg, Uttam, Shulman, Robert J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2015
Materias:	Paediatrics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538270/ https://www.ncbi.nlm.nih.gov/pubmed/26270949 http://dx.doi.org/10.1136/bmjopen-2015-008375

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