Should HFE p.C282Y homozygotes with moderately elevated serum ferritin be treated? A randomised controlled trial comparing iron reduction with sham treatment (Mi-iron)

INTRODUCTION: HFE p.C282Y homozygosity is the most common cause of hereditary haemochromatosis. There is currently insufficient evidence to assess whether non-specific symptoms or hepatic injury in homozygotes with moderately elevated iron defined as a serum ferritin (SF) of 300–1000 µg/L are relate...

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Detalles Bibliográficos
Autores principales: Ong, Sim Yee, Dolling, Lara, Dixon, Jeannette L, Nicoll, Amanda J, Gurrin, Lyle C, Wolthuizen, Michelle, Wood, Erica M, Anderson, Greg J, Ramm, Grant A, Allen, Katrina J, Olynyk, John K, Crawford, Darrell, Kava, Jennifer, Ramm, Louise E, Gow, Paul, Durrant, Simon, Powell, Lawrie W, Delatycki, Martin B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Gastroenterology and Hepatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538285/
https://www.ncbi.nlm.nih.gov/pubmed/26270952
http://dx.doi.org/10.1136/bmjopen-2015-008938

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