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A combination hydrogel microparticle-based vaccine prevents type 1 diabetes in non-obese diabetic mice

Targeted delivery of self-antigens to the immune system in a mode that stimulates a tolerance-inducing pathway has proven difficult. To address this hurdle, we developed a vaccine based-approach comprised of two synthetic controlled-release biomaterials, poly(lactide-co-glycolide; PLGA) microparticl...

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Detalles Bibliográficos
Autores principales:	Yoon, Young Mee, Lewis, Jamal S., Carstens, Matthew R., Campbell-Thompson, Martha, Wasserfall, Clive H., Atkinson, Mark A., Keselowsky, Benjamin G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538389/ https://www.ncbi.nlm.nih.gov/pubmed/26279095 http://dx.doi.org/10.1038/srep13155

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